A preliminary evaluation of a new GeneXpert (Gx) molecular point-of-care test for the detection of Trichomonas vaginalis

S G Badman, L M Causer, R Guy, S N Tabrizi, F Francis, B Donovan D Whiley
23 December 2015. Sex Transm Infect doi:10.1136/sextrans-2015-052384

Trichomonas vaginalis (TV) continue associated with global concerns regarding the prevalence, asymptomatic nature and burden of disease. The scarcity of a portable molecular point-of-care assay to detect TV has shown that many remote or low-resource settings still need to rely on delayed results from central laboratories and management of disease. The new GeneXpert (Gx) TV nucleic acid amplification test (NAAT) was evaluated and compared with an in-house laboratory NAAT to determine if it would be suitable for use at the point of care.

Conclusions: Results suggested the Gx TV assay is easy to use and has suitable overall agreement for sexually transmissible infection (STI) testing at the point of care. To test for three STIs simultaneously, it may be used in combination with the Gx CT/NG assay using this portable and modular-based NAAT platform.

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http://sti.bmj.com/content/early/2015/12/22/sextrans-2015-052384.abstract